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Jipailin,
an anticoagulant and antithrombotic drug
Jipailin
of Jiuyuan, new generation against UFH(unfractionated heparin);Jipailin,warm
your heart by antithrombosis.
In September
1997, Hangzhou Jiuyuan Gene Engineering Co., Ltd. received
New Drug Certificate from the Ministry of Health for the first
Low Molecular Weight Heparin sodium (Proprietary name: Jipailin)
in China. Currently, the expected annual production capacity
is 500 kg in bulk and 10 million in finished ampoules.
[Name]
Chemical name: Injection of Low Molecular Weight Heparin sodium
(LMWH)
Proprietary name: Jipailin
[Description]
Jipailin, produced from porcine intestinal mucosal heparin
by depolymerisation and fractionation, is a new antithrombolic
agent. Its effective composition is low molecular weight heparin
sodium whose mean molecular weight is about 4000. Chemically
it is composed of fragments of glycoaminoglycan(heparin),
sodium salt.
[Preparation]
Jipailin is a sterile, clear and colorless solution for s.c.
or i.v. injection. It has five specifications: 2,500 antiXa-IU(1.0ml),
5,000 antiXa-IU(2.0ml), 3,000 antiXa-IU(0.3ml), 5,000 antiXa-IU(0.5ml)
and 10,000 antiXa-IU(1.0ml).
[Indication]
Prophylaxis and treatment of thromboembolic disorders.
1. To prevent coagulation
and inhibit thrombosis during extracorporeal circulation for
patients with acute or chronic renal failure undergoing haemodialysis
and haemofiltration;
2. Prophylaxis and treatment of deep vein thrombosis(DVT);
3. Treatment of coronary heart disease, unstable angina and
acute myocardial infarction.
Pharmacological
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